Epstein–Barr virus-associated smooth muscle tumors in patients with primary immunodeficiencies

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Cost-effectiveness analysis of subcutaneous immunoglobulin replacement therapy in Iranian patients with primary immunodeficiencies

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Primary Immunodeficiencies Inducing EBV-Associated Severe Illnesses.

Epstein-Barr virus (EBV) is a ubiquitous human gamma-herpesvirus that infects about 95% of the adult population. The majority of primary infections occurs in early childhood and is generally subclinical; it can cause infectious mononucleosis (IM), which is usually a self-limiting lymphoproliferative disorder. However, infection of EBV occasionally results in severe, often lethal diseases, which...

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Epstein–Barr Virus+ Smooth Muscle Tumors as Manifestation of Primary Immunodeficiency Disorders

Epstein-Barr virus positive (EBV+) smooth muscle tumors (SMTs) constitute a very rare oncological entity. They usually develop in the context of secondary immunodeficiency caused by human immunodeficiency virus infection or immunosuppressive treatment after solid organ transplantation. However, in a small fraction of predominantly pediatric patients, EBV+ SMTs may occur in patients with primary...

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ژورنال

عنوان ژورنال: Pediatric Hematology/Oncology and Immunopathology

سال: 2020

ISSN: 2414-9314,1726-1708

DOI: 10.24287/1726-1708-2020-19-4-165-177